Yes. In the Apply rule to field, you choose the scope and status: Campaigns, Ad Sets or Ads, each either Active or Paused. To turn things back on automatically, create a rule with the Paused scope and the Activate action. For example, activate Paused Campaigns every day at 06:00, using the Once a day Frequency with a Run time. Combined with another rule that pauses at night or based on performance, you can set up an automatic on/off schedule. Just be careful with the scope: an Activate rule on Paused Campaigns without Filter by name will reactivate everything paused in the account, including what you paused on purpose.